I have what?
Apart from being hard to declare, Sjögren’s syndrome is an autoimmune condition whose unpredictable nature makes it hard to diagnose and handle.
Those who really receive a timely identification are often left feeling fearful and confused, since they attempt to grasp what it actually means to live with a seemingly mysterious disease.
Unfortunately, many believe they have no other option than to go down the rabbit hole of lifelong drugs with unrelenting side effects.
You will wonder if additional choices even exist….
In case you’re trying to find a different choice but don’t know where to begin, you are in the perfect place.
Continue reading, as we dip right into that which contributing factors ignite this disease, what function the intestine plays in turning it to, what you could do to conquer Sjögren’s obviously and a lot more.
What’s Sjögren’s Syndrome?
Sjögren’s syndrome (pronounced SHOW-grins) is the 2nd most frequent autoimmune disease in the world. It primarily impacts the salivary (mouth) and lacrimal (eye) glands, which under ordinary circumstances help produce moisture in the form of tears and saliva.
For Those Who Have Sjögren’s, the body fails to produce enough moisture…
That May Lead to a whole host of symptoms like:
- Dry mouth and eyes
- Issue swallowing/eating
- Blurred vision/ Burning feeling in your eyes
- Hoarseness/non-productive cough
- Recurrent mouth infections
Even not as frequent, Sjögren’s can actually affect the entire body. Sometimes, it may lead to systemic symptoms such as fatigue, rashes, dry skin and joint soreness. In one analysis, 67 percent of patients reported having an abnormal amount of exhaustion on daily basis.
As many as 4 million individuals live with Sjögren’s – a condition called after the swedish ophthalmologist Henrik Sjögren who explained the symptoms in 1933. Regardless of the range of individuals afflicted by this illness, it’s uncommon for two individuals to present with the exact same symptoms.
And this is why a suitable examination is so important in regards to getting the ideal diagnosis.
Diagnostic Tools to Sjögren’s Outcomes
No single diagnostic evaluation is sufficient to confirm a diagnosis, but rather a succession of approaches are utilized. Performing a physical examination and reviewing the patient’s medical history is a good starting place, followed closely by an Antinuclear Antibody (ANA) blood test.
A particular X-ray of the salivary glands, called a sialogram, can help determine if the salivary gland or duct is blocked. A biopsy of the salivary glands might help ascertain whether inflammation is present, and if so, the severity. Most reachable for a biopsy are the small salivary glands just under the inner surface of the lip – which is a test commonly known as a lip biopsy.
The Schirmer tear test is a test used to determine the degree of moisture from the eye and acts as a fantastic indicator of how far the eyes are being influenced.
Individuals diagnosed are classified as either primary or secondary. Principal Sjögren’s syndrome tends to be aggressive and happens in those people who do not have some other autoimmune conditions. Secondary Sjögren’s happens in people who already have another autoimmune disorder using scleroderma, lupus, and Rheumatoid Arthritis being the most frequent.
Most individuals are well in their 40’s before they are diagnosed and women are 9 times more likely to develop the disease than men.
Complications of Sjögren’s Syndrome
In some cases, it’s possible for people suffering from Sjögren’s to experience complications from different areas like the kidneys and lymph nodes.
It’s estimated that 9–24 percent of patients having Sjögren’s suffer with lung troubles, which can lead to increased risk of mortality.
The most serious complication of Sjögren’s is Non-Hodgkin’s Lymphoma (NHL) – a type of cancer that starts in lymphatic cells (those cells are a part of the immune system). For all those who have Sjögren’s, it happens most commonly in the salivary glands.
The probability of developing NHL is equal for both secondary and primary Sjögren’s and some studies estimate the risk to be 44 times greater than that detected in a wholesome population.
Persistent enhancement of a significant salivary gland should be carefully and regularly observed by your physician and researched further if the dimension changes.
Other symptoms to be aware of are:
- Unexplained fever and weight loss
- night sweats
- unrelenting fatigue
- reddened patches on skin
The Genetic Link in Sjögren’s Infection
As seen in our autoimmune series of articles, nearly every state has a genetic element and Sjögren’s is not any different.
Research has discovered the STAT4 gene version related to rheumatoid arthritis and lupus is also associated with chief Sjögren’s syndrome (pSS). At a recent case control study, the probability of developing Sjogren’s was seven times higher one of first-degree relatives with autoimmune disease compared to management group.
Another study replicated these observations by showing that first-degree loved ones of Sjogren’s patients had an increased risk of creating the illness (as well as systemic lupus, RA, systemic diseases, along with type 1 diabetes) compared to the general population.
Both studies above, as well as several other people, strongly suggest a genetic effect in the growth of Sjögren’s syndrome. Researchers also recognize the genes do not act independently. It is probably the mix of ecological exposures and genetics are what evoke an autoimmune disease.
Contributing Factors in Progress of Sjögren’s Syndrome
Factors which result in the onset of autoimmune disorders are crucial to understanding how to manage the condition naturally.
The most frequent contributing factors in Sjögren’s syndrome are:
Viral Infection – Researchers discovered that a chronic cytomegalovirus (CMV) infection could cause the growth of Sjögren’s. The persistence of CMV may commence tissue degradation in genetically susceptible people by assaulting the salivary and lacrimal glands via antigenic expression. Finally, this can cause the manifestation of Sjogren’s syndrome.
Studies also show a correlation involving an Epstein Barr Virus (EBV) infection and the pathogenesis (development of disorder ) of both Sjögren’s Syndrome.
Hormones – Since Sjögren’s syndrome displays such a large female prejudice, genetic makeup is an intuitive area to examine. This study reveals low degrees of the anti inflammatory sexual hormone DHEA is associated with the symptoms found in main Sjögren’s syndrome along with dry mouth symptoms diminished during DHEA treatment.
Anxiety – Persistent physical, emotional and mental stress all have the ability to lower the body’s immune capacities . Not only does this aggravate chronic symptoms, however, also welcome different infections (like those mentioned above). Those suffering from Sjögren’s say the number one cause of a hay or a relapse is a stressful event. When it’s taking a short walk or integrating a daily meditation routine, discovering ways to destress is a important part of managing the problem.
Sjögren’s Syndrome and the Digestive System
Simply place, Sjögren’s syndrome can wreak havoc on the digestive tract and impair quality of your life. Researchers estimate over 25 percent have moderate to severe gastrointestinal issues.
The most common digestive complaints of those with Sjögren’s are:
Constipation – Sufficient moisture is required to have a perfect, type 4 on the bristol feces chart. Constipation issues might be a consequence of the diminished fluid in the intestinal tract if less saliva is produced. A possible connection between the effect of Sjögren’s and the smooth muscle that propels food along the intestines is now being analyzed, but there aren’t any definitive results at the time.
Chronic Atrophic Gastritis – Also called inflammation of the gut lining, gastritis frequently results from the gradual deterioration of their protective mucosa from the gut. This may lead to a decrease in stomach acid, which is important for optimum digestion. Studies reveal gastritis occurs more commonly in Sjögren’s syndrome patients versus wholesome individuals.
Gastroesophageal Reflux (GERD) – Appropriate stomach acid amounts are needed to prevent infections at bay and to correctly break down foods. In contrast to popular belief, it is really the lack of stomach acid that is probably the reason for GERD (vs. too much acid). Testing your acid levels and supplementing with Betaine HCl if mandatory is a great place to begin in getting to the bottom of acid reflux.
Coeliac Disease (CD) – More commonly known as Celiac diseasethis problem is characterized by inflammation of the small intestine and villus atrophy which is in part because of gluten exposure. A study discovered that Celiac disease can be identified in 5 34 Sjögren’s syndrome patients (14.7%).
Irritable Bowel Syndrome (IBS) – IBS is characterized by pain or discomfort in the stomach region along with gut changes and happens in around 15% of the population. In patients with Sjögren’s syndrome, IBS has been proven to influence 39-65% versus 9-15% in healthy controls. Physicians and researchers have identified that a root cause of IBS – in up to 84 percent of IBS instances it is SIBO (small intestine bacterial vaginosis ).
It may be overwhelming to see all of these complaints as separate ailments wholly independent of one another. The fantastic news is they’re actually all linked.
The Leaky Gut – Autoimmune Link
Leaky gut areas an unrelenting need in the immune system. This is especially harmful for those battling an autoimmune condition with an immune system working overtime.
One expert summarized it this way:
“Leaky gut syndrome is virtually always related to autoimmune disease. In fact, reversing signs of autoimmune disease is dependent on curing the lining of the gastrointestinal tract. Any other treatment is merely symptom suppression.” – Dr. Jill Carnahan, MD
Another specialist, Alessio Fasano, M.D., has been in the forefront of pancreatic disease study and published a paper titled”Leaky Gut and Autoimmune Diseases.”
His findings have shown that for an autoimmune disease to develop, 3 states must all exist :
- An hereditary predisposition to autoimmunity (i.e. STAT4 gene at Sjögren’s)
- An exposure to this environmental cause (i.e. Viral Infection)
- Improved intestinal permeability (a.k.a. Leaky Gut Syndrome)
It may be unsettling to notice this a leaky gut plays a major part in the creation of autoimmunity… but we have good news. It is 1 factor that’s fully in our hands and, beyond that, it could be healed using all the right plan.
Talking of a plan, allow ’s’ consider exactly what mainstream medicine offers.
Medical Treatment for Sjögren’s – Hurtful or Useful?
Prescription drugs remain the cornerstone for the conventional remedy of Sjögren’s syndrome. The target is to take care of the many symptoms that can arise, in dry eyes and mouth to joint pain and fatigue.
The most popular medicine used to deal with systemwide complications is methotrexate (Trexall), an aggressive drug designed to suppress the immune system. Many patients do report symptoms, but are not easy to point out the side effects too.
The most common side effects of methotrexate are nausea, vomiting, stomach pain, drowsiness, temporary hair loss and nausea. And though this drug is shown to decrease the main signs of dry mouth and eyes, this research reveals target parameters did not change.
What exactly does that mean?
It means that although symptoms seemed to enhance, actual evaluation measures showed no distinction. To put it differently, it can be considered as a band-aid form of treatment.
Studies such as this (along with the negative effects of most drugs) leave us with several questions, when it comes to finding the Perfect treatment plan:
- What kind of therapy do I need (quick fix vs. continuing treatment)
- Are the side effects of medications worthwhile?
- Just how much am I prepared to spend on drugs?
- Exactly what occurs when the drug no longer works?
- Do natural remedies exist?
Until now, you may have thought the medical route was the only alternative. But, thankfully, there’s another manner.
How To Turn Off Autoimmune Disease
The ability of this human microbiome just cannot be refused.
Hippocrates, the famous Greek physician, was conscious of the even 2,000 years ago when he said”all disease starts in the gut.” As early and current wisdom suggests, the very best place to start is the gut and we’re here to help you do just that.
Jordan and Steve hosted on a free webinar called,”How To Switch Your Autoimmunity and Restore a Healthy Immune System.”
It’s completely FREE and you can register for your seat here: https://healthygut.com/autoimmune-webinar/
The topic of autoimmunity is complicated and the total amount of info out there may be overpowering. That is why we’ve completed the job for you and are grateful to encourage you on this journey – all you need to do is register here.
– Lori Jo
P.S. – Don’t worry if you can not attend live, we will send you some free replay another day when you register here.
P.P.S – Let’s know what you are struggling with at the remarks below.
The article Sjögren’s Syndrome: What Causes It And How To Conquer It Obviously appeared first on Healthy Gut Company.